The CCRM Fertility clinic at 10290 Ridgegate Circle in Lone Tree, Colorado is the original flagship location of what became one of North America's most recognized IVF networks. Founded by Dr. William Schoolcraft, CCRM Lone Tree has for decades served as the organization's center of clinical and laboratory excellence — a reputation built on high success rates, advanced preimplantation genetic testing, and a research-forward approach to reproductive medicine. The Lone Tree campus holds a 3.6-star rating across 260 patient reviews; reviewers consistently praise clinical outcomes and physician expertise while occasionally citing challenges navigating a high-volume practice. Colorado does not have a state fertility insurance mandate. For a complete overview of fertility providers across the state, see the Colorado fertility clinics directory.
Physicians and Clinical Team
CCRM Lone Tree houses some of the most published and credentialed reproductive endocrinologists in the United States. The founding physician, Dr. William Schoolcraft, is internationally recognized for innovations in embryo culture, blastocyst transfer, and PGT protocols. The broader physician team at the Lone Tree campus includes multiple fellowship-trained REI specialists who subspecialize in complex cases such as poor ovarian response, recurrent implantation failure, recurrent pregnancy loss, and oncofertility. Embryologists at the Lone Tree lab are among the most experienced in the country, having performed thousands of IVF cycles. Specific physician availability changes as the network grows; visit ccrmivf.com or call (303) 788-8300 for current provider information.
Services and Treatments
- IVF with ICSI
- Preimplantation genetic testing for aneuploidy (PGT-A) and monogenic disease (PGT-M)
- Comprehensive chromosomal screening (CCS)
- Egg freezing (elective and medical fertility preservation)
- Embryo freezing and frozen embryo transfer
- Donor egg IVF, donor embryo transfer
- Gestational carrier coordination
- Recurrent pregnancy loss evaluation and management
- Diminished ovarian reserve protocols
- Male factor infertility evaluation (including surgical sperm retrieval)
- Endometriosis and uterine factor evaluation
- ERA (endometrial receptivity analysis) testing
- Second-opinion consultations for failed IVF cycles
- Oncofertility preservation
Laboratory and Success Rates
CCRM Lone Tree's embryology laboratory is considered one of the premier ART labs in the world, known for its work on extended blastocyst culture, vitrification, and biopsy techniques for genetic testing. The lab's culture conditions and quality control protocols have been the subject of peer-reviewed publications. Prospective patients should request the clinic's most current age-stratified success data during their consultation. Patients should review the most current cycle-level data published by the CDC's ART Surveillance program and the SART Clinic Summary Report.
Patient Experience
The Ridgegate Circle campus is located in the Lone Tree master-planned community south of Denver, close to the Park Meadows corridor and easily accessible from I-25. The facility is modern and well-appointed, with a dedicated patient care philosophy that includes nurse coordinators assigned to each patient's cycle. Patients traveling from out of state — and CCRM Lone Tree sees a significant volume of traveling patients who have had failed cycles elsewhere — will find the Denver metro area straightforward to navigate, with Denver International Airport about 40 minutes away.
The clinical experience at a high-volume flagship can feel more structured and less intimate than a smaller boutique practice, and some patient reviews reflect that tradeoff. Patients who are highly engaged with their own data, who want access to cutting-edge genetic testing options, or who are seeking a second opinion after a failed cycle at another clinic often find CCRM Lone Tree to be the right fit. The practice has dedicated coordinators for out-of-state and international patients to help manage remote monitoring and minimize the number of trips to Colorado.
Support services at the Lone Tree campus include dedicated nurse-coordinators, financial counselors, and access to mental health referrals. The clinic participates in ongoing clinical research, and some patients may qualify for study protocols.
Considering At-Home Insemination?
Not every fertility journey begins in a clinic. At-home intracervical insemination (ICI) is a lower-cost, private option that suits patients with no known fertility diagnosis — including single parents by choice, same-sex couples, and people who want to try a few cycles before committing to clinical treatment.
At-home insemination kits like those from MakeAMom come with step-by-step instructions designed for donor or partner sperm. Kits are a one-time purchase that can be reused until conception succeeds, require no clinic visit, and arrive in plain, discreet packaging. Many patients use them as a first step while working toward a fertility consultation — or alongside ovulation tracking while they wait for an appointment slot.
If you have a known fertility diagnosis, have been trying for 12 months without success (six months if you're over 35), or your physician has already recommended IUI or IVF, a board-certified reproductive endocrinologist is the right next step.
Insurance and Financing
Colorado does not mandate fertility insurance coverage, though some larger employers with Colorado-based plans voluntarily include IVF benefits. CCRM offers multi-cycle package pricing and works with financing companies including CapexMD. Patients coming from states with mandated coverage (such as Massachusetts, New Jersey, or Illinois) may be able to use their home-state insurance benefits at CCRM if their plan is administered under those state rules — patients should verify this with both their insurer and the clinic. CCRM's financial counselors are equipped to walk patients through all available options.
Frequently Asked Questions
Why do patients travel from out of state to CCRM Lone Tree? CCRM's flagship location is sought out for complex cases — including poor ovarian response, recurrent implantation failure, and recurrent pregnancy loss — because of the lab's reputation for high-quality embryo culture and advanced genetic testing. Some patients also seek second opinions after unsuccessful cycles at other clinics.
What is PGT-A and why does CCRM emphasize it? Preimplantation genetic testing for aneuploidy (PGT-A) screens embryos for chromosomal abnormalities before transfer. CCRM has been a leading advocate of PGT-A as a tool to reduce miscarriage rates and improve single-embryo transfer success. Your physician will discuss whether PGT-A is appropriate for your specific case.
Is CCRM Lone Tree different from other CCRM network locations? Yes and no. All CCRM network clinics follow standardized protocols developed at the Lone Tree flagship. However, the Lone Tree campus has the network's largest lab infrastructure, the most tenured physicians, and the longest institutional track record. Some patients specifically seek out the flagship for cases requiring maximum lab capability.
How far in advance should I schedule a new patient appointment? New patient appointment availability fluctuates. During peak times, waits of four to eight weeks are not uncommon. Patients with urgent timeline concerns (such as pending cancer treatment) should communicate that at the time of scheduling, as expedited appointments may be possible.