Isaac Kligman, MD — An Honest Editorial Review
Within fertility clinics in New York, Weill Cornell Medicine's Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine has run one of the Northeast's largest academic IVF programs for more than three decades. Dr. Isaac Kligman completed his REI fellowship there in 1995 under Dr. Zev Rosenwaks and has been on the faculty ever since, now at 1305 York Avenue, 6th Floor.
Dr. Kligman is Professor of Clinical Obstetrics and Gynecology and Professor of Clinical Reproductive Medicine at Weill Cornell Medical College, and is dual board-certified in OB/GYN and in Reproductive Endocrinology and Infertility by the American Board of Obstetrics and Gynecology. Within the Perelman-Cohen faculty, his published record leans heavily toward ovarian-stimulation protocols, age-related IVF outcomes, ICSI, and donor-oocyte recipient cycles.
Training and Credentials
Dr. Kligman earned his MD from Universidad Javeriana in Bogotá, Colombia (1981) and completed OB/GYN training both in Bogotá and at the University of Maryland Medical Center (1992). He completed a research fellowship in Reproductive Biology and Endocrinology at the University of Pennsylvania's Perelman School of Medicine in 1989, followed by his clinical REI fellowship at the Perelman-Cohen Center for Reproductive Medicine (1995). His PubMed publications span decades of work on implantation, stimulation protocols, and assisted reproduction.
Services and Specialties
Services through Dr. Kligman's practice include:
- In Vitro Fertilization (IVF) with ICSI and frozen embryo transfer
- Intrauterine Insemination (IUI) and ovulation induction
- Egg freezing and embryo cryopreservation
- Donor egg IVF and third-party reproduction
- Ovarian-stimulation protocols for diminished ovarian reserve
- Diagnostic and operative laparoscopy and hysteroscopy
- Endometriosis and tubal-factor infertility
Success Rates and Lab Quality
Weill Cornell reports outcomes at the program level to SART; see the SART Clinic Summary Report (ClinicPKID 1947) and the CDC ART Success Rates database. Because Dr. Kligman sees a meaningful share of women over 40, compare age-banded live-birth rates rather than headline averages — our how to read IVF success rates and IVF success rates by age guides walk through the common traps.
Patient Experience
Dr. Kligman's Google rating is 5.0/5 across roughly 27 reviews, which is consistent with the broader Perelman-Cohen faculty pattern. Recurring themes in public reviews point to patient, detail-oriented protocol conversations — expected from a physician whose published work focuses on individualized ovarian-response tuning — and to continuity of care across multiple cycles. The York Avenue location is near the Q and 6 trains; stimulation-cycle patients should budget for daily monitoring.
Considering At-Home Insemination?
Not every fertility journey begins in a clinic. At-home intracervical insemination (ICI) is a lower-cost, private option that suits patients with no known fertility diagnosis — including single parents by choice, same-sex couples, and people who want to try a few cycles before committing to clinical treatment.
At-home insemination kits like those from MakeAMom come with step-by-step instructions designed for donor or partner sperm. Kits are a one-time purchase that can be reused until conception succeeds, require no clinic visit, and arrive in plain, discreet packaging. Many patients use them as a first step while working toward a fertility consultation — or alongside ovulation tracking while they wait for an appointment slot.
If you have a known fertility diagnosis, have been trying for 12 months without success (six months if you're over 35), or your physician has already recommended IUI or IVF, a board-certified reproductive endocrinologist is the right next step.
Insurance and Cost in New York
New York's 2020 fertility mandate requires state-regulated large-group commercial plans to cover up to three IVF cycles per lifetime; self-funded employer (ERISA) plans are exempt. Weill Cornell contracts with most major commercial insurers. See our fertility insurance mandates by state guide and IVF cost by state breakdown before your financial consult.
Location and Contact
Address: 1305 York Ave, 6th Floor, New York, NY 10021 Phone: (646) 962-2764 Website: weillcornell.org/isaackligman
Frequently Asked Questions
What is Dr. Kligman's subspecialty focus within the Perelman-Cohen faculty? His published work concentrates on ovarian-stimulation protocols, ICSI, donor-oocyte recipient cycles, and age-related IVF outcomes — areas that overlap substantially with patients who have diminished ovarian reserve or are approaching the upper end of the reproductive age range.
Does Dr. Kligman see patients for second opinions after failed cycles elsewhere? The Perelman-Cohen Center regularly accepts patients who have completed cycles at other programs. Forwarding prior records ahead of the first visit is typical.
How long has Dr. Kligman been at Weill Cornell? Since completing his REI fellowship there in 1995 — roughly three decades on the same academic faculty.
Editorial note: Independently researched by the Fertlo editorial team; not sponsored. See our editorial policy.