Kofinas Fertility Group is a well-known New York City fertility practice associated with physician Dr. Jason Kofinas. The clinic operates in New York City — one of the most competitive and clinically advanced fertility markets in the United States — and has developed a particular reputation for treating patients with recurrent pregnancy loss and immunologic infertility, including those who have had failures at other programs. For a complete overview of fertility care options statewide, visit the New York fertility clinics directory.
Physicians and Clinical Team
Dr. Jason Kofinas is a reproductive endocrinologist who completed training in OB/GYN and subsequently specialized in reproductive endocrinology and infertility. The practice bearing his name reflects a physician-centered, subspecialty-focused model in which the treating physician is directly involved in complex clinical decision-making for each patient.
Kofinas Fertility Group is particularly associated with immunologic approaches to infertility and recurrent pregnancy loss — an area of ongoing research in the field that examines the role of immune system dysregulation (including natural killer cell activity, autoantibody profiles, and inflammatory cytokines) in implantation failure and miscarriage. This specialization attracts patients who have experienced unexplained repeated IVF failures or multiple miscarriages and are seeking evaluation beyond conventional REI workup.
The practice also works with a skilled embryology team and clinical nursing staff to support the full spectrum of IVF treatment, third-party reproduction, and diagnostic services.
Services and Treatments
Kofinas Fertility Group provides comprehensive fertility care with particular depth in complex cases:
- IVF (In Vitro Fertilization) — stimulated and natural-cycle IVF with individualized protocols
- IUI (Intrauterine Insemination) — medicated and natural-cycle for appropriate candidates
- Egg Freezing — elective and medical fertility preservation
- Preimplantation Genetic Testing (PGT-A/PGT-M) — chromosomal aneuploidy screening and monogenic disease testing
- Frozen Embryo Transfer (FET) — natural-cycle and hormone-medicated
- Donor Egg IVF — including coordination with donor agencies or known donors
- Donor Sperm Services
- Male Infertility Evaluation — semen analysis and hormonal assessment
- Recurrent Pregnancy Loss Workup — immunologic, thrombophilic, anatomical, and genetic evaluation
- Immunologic Infertility Treatment — tailored immune modulation protocols for implantation failure and recurrent loss
- Gestational Surrogacy Coordination
- Reproductive Endocrine Disorders — PCOS, diminished ovarian reserve, thyroid and adrenal management affecting fertility
Laboratory and Success Rates
Kofinas Fertility Group coordinates with established embryology laboratories, and the clinical approach emphasizes patient-specific tailoring of stimulation, transfer, and supportive treatment protocols. The program's emphasis on immunologic evaluation means patients often undergo more extensive diagnostic testing prior to treatment than at a conventional REI practice — including immune panels that inform whether protocols such as intralipid infusions, corticosteroids, or other immune-modulating approaches are warranted.
Reported CDC and SART outcome data for the program reflects the totality of cycles performed and should be contextualized: a practice that selectively treats difficult, multi-failure patients may report different statistics than a program treating primarily first-time IVF patients.
Patients should review the most current cycle-level data published by the CDC's ART Surveillance program and the SART Clinic Summary Report.
Patient Experience
New York City patients seeking Kofinas Fertility Group's care are often patients who have not succeeded at other programs — a population that requires significant clinical patience, individualized attention, and clear communication about the evidence base for each proposed intervention. The practice's physician-led model supports this level of engagement.
Access in Manhattan is generally good by subway, and many patients commute from Brooklyn, Queens, New Jersey, or Long Island. For patients traveling from outside the tri-state area who are specifically seeking the clinic's expertise in immunologic infertility, coordination of travel with monitoring and retrieval schedules is important to discuss at the initial consultation.
Considering At-Home Insemination?
Not every fertility journey begins in a clinic. At-home intracervical insemination (ICI) is a lower-cost, private option that suits patients with no known fertility diagnosis — including single parents by choice, same-sex couples, and people who want to try a few cycles before committing to clinical treatment.
At-home insemination kits like those from MakeAMom come with step-by-step instructions designed for donor or partner sperm. Kits are a one-time purchase that can be reused until conception succeeds, require no clinic visit, and arrive in plain, discreet packaging. Many patients use them as a first step while working toward a fertility consultation — or alongside ovulation tracking while they wait for an appointment slot.
If you have a known fertility diagnosis, have been trying for 12 months without success (six months if you're over 35), or your physician has already recommended IUI or IVF, a board-certified reproductive endocrinologist is the right next step.
Insurance and Financing
New York State requires large group insurance plans (100+ employees) to cover medically necessary fertility treatment, including IVF, for eligible patients. Under this mandate:
- Up to three IVF cycles per lifetime are covered for qualifying patients
- The definition of infertility includes same-sex couples and individuals
- Egg freezing for medical necessity is covered under applicable plans
- Self-insured (ERISA) plans are exempt from the state mandate
For patients seeking Kofinas Fertility Group's specialized immunologic treatment, some of the diagnostic testing (immune panels, repeat testing) may be considered experimental by some insurers and may not be covered even under a comprehensive fertility benefit. Patients should verify coverage for specific tests and treatments with their insurer before proceeding.
Frequently Asked Questions
What is immunologic infertility and how does Kofinas Fertility Group approach it? Immunologic infertility refers to situations in which the immune system may be interfering with embryo implantation or early pregnancy maintenance. This is a specialized and evolving area of reproductive medicine. The practice evaluates immune markers and may implement immune-modulating protocols — such as intralipid infusions, low-dose corticosteroids, or other therapies — as part of individualized treatment plans. Patients considering this approach should understand the evidence base for specific interventions and discuss the expected benefits and limitations with their physician.
Is Kofinas Fertility Group appropriate for a first-time IVF patient? Yes. While the practice has a reputation for treating complex cases, it provides a full spectrum of fertility care including standard IVF for patients without prior treatment failures. The first-consultation evaluation will determine the appropriate diagnostic and treatment pathway for each individual.
How many cycles does the New York IVF mandate cover, and does it cover donor egg cycles? New York's mandate covers up to three IVF cycles per lifetime for qualifying patients under large-group plans. Coverage for donor egg cycles may vary by plan — some plans cover the recipient's medical costs but not the donor's compensation. A fertility benefits coordinator at the practice can help clarify coverage.
Can I get a second opinion at Kofinas Fertility Group after failing at another program? Yes. The practice commonly evaluates patients who have experienced failed IVF cycles or recurrent pregnancy loss at other programs. Bringing all prior records — cycle reports, embryology data, pathology results, and prior immune testing — to the consultation will allow the physician to conduct a thorough review and propose whether a modified approach might improve outcomes.