John C. Jarrett II, M.D. (Carmel, IN) — Fertlo Editorial Review
4.8 stars / 315 reviews · 10610 N Pennsylvania St, Suite 101, Carmel, IN 46280
When a physician has been practicing reproductive endocrinology in the same metropolitan area for four decades, the evidentiary bar shifts from promise to track record. John C. Jarrett II, M.D. performed Indiana's first successful IVF cycle in 1985 and has since anchored the Indianapolis–Carmel REI corridor through every major technological transition the field has seen — from early embryo cryopreservation to preimplantation genetic testing to high-volume SART outcomes reporting. Patients considering his practice, which operates in Carmel as Jarrett Fertility Group (now clinically aligned with Indiana Fertility Institute), are looking at one of a small number of Midwestern REIs whose career predates the modern IVF era entirely.
About the Physician
Dr. Jarrett completed his undergraduate training at Princeton University and earned his medical degree at Case Western Reserve University School of Medicine. He trained in obstetrics and gynecology at the University of Michigan Medical Center, then completed a fellowship in reproductive endocrinology and infertility (REI) at the University of Illinois at Chicago. He holds dual board certification from the American Board of Obstetrics and Gynecology in both general OB/GYN and the REI subspecialty — the defining credential for reproductive endocrinologists and the one patients can confirm independently at abog.org.
His career milestones read like a chronology of Indiana's reproductive medicine history. In 1985, he established the state's first successful IVF program at Women's Hospital in Indianapolis. He performed Indiana's first successful GIFT (gamete intrafallopian transfer) and ZIFT (zygote intrafallopian transfer) procedures, launched the state's first embryo cryopreservation program, and initiated Indiana's first clinical egg donation program. He is a Charter Member of the Society for Assisted Reproductive Technology (SART) and a Charter Participant of the National IVF Registry — distinctions that place him among the physicians who built the outcomes-tracking infrastructure the U.S. fertility field still relies on today. Castle Connolly has recognized him as a Top Doctor for 16 consecutive years, including 2026. He has also co-authored The Fertility Guide.
Volume Signals
Over more than four decades of continuous REI practice, Dr. Jarrett has personally performed more than 13,000 assisted reproductive procedures — a cumulative volume few REIs in the Midwest have matched. His practice reported 1,204 total ART cycles in its most recent SART clinic summary (2023), which places it in the upper tier of Midwestern IVF centers by annual volume and is large enough to generate statistically credible age-stratified outcomes. The practice is also a Castle Connolly–recognized center, and its current REI team has been designated Inception Fertility's Clinic of the Year (2025) within the Prelude Network.
Services Offered
Dr. Jarrett and his team deliver the full spectrum of assisted reproductive technology and reproductive surgery:
- In vitro fertilization (IVF) with conventional insemination and ICSI for male-factor cases
- Fresh and frozen embryo transfer (FET) protocols, including programmed and modified natural cycles
- Preimplantation genetic testing — PGT-A for aneuploidy, PGT-M for monogenic disorders, PGT-SR for structural rearrangements
- Egg freezing for elective and medically indicated (oncofertility) preservation
- Donor egg IVF with both known and anonymous donors — a program Dr. Jarrett originated in Indiana
- Gestational carrier (surrogacy) cycles with full medical and legal coordination
- Intrauterine insemination (IUI) with natural or medicated cycles
- Reproductive surgery for endometriosis, fibroids, polyps, adhesions, and tubal disease
- Male-factor evaluation, including surgical sperm retrieval (TESA/MESA)
- Ovulation induction with clomiphene, letrozole, and gonadotropins for PCOS and anovulation
- Fertility preservation for cancer patients, coordinated with oncology teams
What This Practice Is
Jarrett Fertility Group is a physician-led private REI practice operating out of a dedicated Carmel office on North Pennsylvania Street, with a state-licensed, CAP-accredited, CLIA-certified embryology laboratory on-site. The lab is certified to Class 100 cleanroom standards — the highest particulate-control rating used in ART embryology — and is directed by a PhD-level lab director. The practice is a SART-member clinic, meaning annual outcomes are submitted to the national registry and published publicly via sartcorsonline.com. That matters: SART membership commits a clinic to uniform data reporting methods and outcomes transparency that non-member fertility offices are not bound by.
Because IVF outcomes depend heavily on embryology execution — not just physician judgment — the combination of an on-site SART-reporting lab and a four-decade clinical career is unusual in the Midwest. For background on how to read the SART tables meaningfully, our guide to how to read IVF success rates walks through the age-stratified cumulative-birth figures and common misinterpretations.
Indiana Insurance Context
Indiana has historically had no comprehensive state fertility-insurance mandate, which has shaped how Indianapolis-area REI practices structure financing. Patients typically pay out of pocket or rely on employer-sponsored benefits that vary widely by plan. In 2025, limited fertility coverage legislation (HB1205) began to reach some state-regulated plans, but self-funded ERISA plans — which cover a majority of large-employer populations — remain unaffected by state law. Our fertility insurance mandates by state 2025 guide outlines what Indiana patients can realistically expect and which plan categories are affected.
The practice offers BUNDL multicycle packages and works with fertility-specific lenders (LendingClub, CapexMD, Future Family) to smooth the out-of-pocket burden across multiple retrieval or transfer attempts.
Patient Experience
A 4.8-star average across 315 reviews is a credible signal for a single-physician-anchored REI practice — not a hospital department where ratings are diluted across hundreds of clinicians. Reviewers repeatedly mention Dr. Jarrett's direct availability after difficult cycles, his willingness to explain protocol changes personally, and the continuity patients experience across what is often a multi-year journey. Staff continuity and laboratory responsiveness are consistent themes.
Considering At-Home Insemination?
Not every fertility journey begins in a clinic. At-home intracervical insemination (ICI) is a lower-cost, private option that suits patients with no known fertility diagnosis — including single parents by choice, same-sex couples, and people who want to try a few cycles before committing to clinical treatment.
At-home insemination kits like those from MakeAMom come with step-by-step instructions designed for donor or partner sperm. Kits are a one-time purchase that can be reused until conception succeeds, require no clinic visit, and arrive in plain, discreet packaging. Many patients use them as a first step while working toward a fertility consultation — or alongside ovulation tracking while they wait for an appointment slot.
If you have a known fertility diagnosis, have been trying for 12 months without success (six months if you're over 35), or your physician has already recommended IUI or IVF, a board-certified reproductive endocrinologist is the right next step.
When to Consult
Typical REI consult triggers that warrant scheduling with Dr. Jarrett or his team:
- 12 months of unprotected intercourse without conception if you are under 35
- 6 months of trying without conception if you are 35 or older
- 3 months or less if you are over 40 or have known risk factors
- Two or more recurrent pregnancy losses
- Known or suspected endometriosis, PCOS, premature ovarian insufficiency, or diminished ovarian reserve
- Male-factor findings on semen analysis (low count, motility, or morphology)
- Prior pelvic surgery, tubal disease, or significant uterine pathology
- Oncofertility preservation before gonadotoxic treatment
- Single-parent-by-choice or LGBTQ+ family building using donor gametes or a gestational carrier
- Interest in elective egg freezing for reproductive autonomy
Our preconception health primer covers the evaluations and lifestyle steps worth completing before that first appointment.
Location and Contact
Jarrett Fertility Group (John C. Jarrett II, M.D.) 10610 N Pennsylvania Street, Suite 101 Carmel, IN 46280 Phone: (317) 575-6565 Website: fertilityindy.com
The Carmel office sits in the North Pennsylvania medical corridor, accessible from US-31 and the I-465 loop. For comparative context on other central Indiana REI options, see our Indiana fertility clinic directory.
Frequently Asked Questions
Is Dr. Jarrett board-certified in reproductive endocrinology?
Yes. Dr. Jarrett is dual-board-certified by the American Board of Obstetrics and Gynecology in both general obstetrics and gynecology and in reproductive endocrinology and infertility — the REI subspecialty. You can independently confirm his certification status at abog.org/verify-a-physician.
Does Jarrett Fertility Group report outcomes to SART?
Yes. The practice is a SART-member clinic and submits annual outcomes to the Society for Assisted Reproductive Technology. Public clinic summary reports are available at sartcorsonline.com. Age-stratified live birth rates and cycle volumes are the most clinically meaningful figures; our how to read IVF success rates guide explains how to interpret them.
How long has Dr. Jarrett been practicing REI?
Dr. Jarrett has been in continuous REI practice in the Indianapolis–Carmel area since the early 1980s. He established Indiana's first successful IVF program in 1985 and has personally performed more than 13,000 assisted reproductive procedures across his career.
Does Indiana require insurance to cover IVF?
Indiana has historically had no comprehensive fertility-insurance mandate. Limited 2025 legislation touches some state-regulated plans, but self-funded ERISA plans — which cover most large-employer populations — remain unaffected. Our fertility insurance mandates by state 2025 guide covers the current landscape and what questions to ask your HR department.
What fertility services does Dr. Jarrett offer beyond IVF?
The full REI menu: IUI, ovulation induction, egg freezing, donor-egg cycles, gestational carrier cycles, preimplantation genetic testing (PGT-A, PGT-M, PGT-SR), reproductive surgery for endometriosis and fibroids, and male-factor evaluation including surgical sperm retrieval. Oncofertility preservation and LGBTQ+ family-building pathways are also part of the standard program.
Where can I learn more about IVF outcomes and ART generally?
The Centers for Disease Control and Prevention publishes annual national ART surveillance data at cdc.gov/art. The American Society for Reproductive Medicine (asrm.org) maintains patient-facing guidance on diagnostic and treatment pathways. For peer-reviewed literature, PubMed indexes the primary research underlying current protocols.
Editorial note: Independently written by the Fertlo editorial team; not sponsored. See our editorial policy.