Knoxville Gynecologic Cancer Specialists, P.C. is a specialty gynecologic oncology practice located at 10810 Parkside Drive, Suite 200, in Knoxville, Tennessee — in the Farragut/west Knoxville corridor of Knox County. Knoxville is East Tennessee's largest city and serves as a regional medical hub for communities throughout Appalachian Tennessee and neighboring states. Gynecologic oncologists provide specialized surgical and medical management of gynecologic cancers, and their expertise is sometimes relevant to fertility-related concerns — particularly for patients who have been diagnosed with a gynecologic malignancy and wish to explore fertility-sparing treatment approaches, or for those whose reproductive anatomy has been affected by prior oncologic treatment. Patients in Tennessee seeking dedicated fertility care can explore providers in the Tennessee fertility clinics directory.
Physicians and Clinical Team
Knoxville Gynecologic Cancer Specialists is a surgical subspecialty practice staffed by gynecologic oncologists — OB-GYN physicians who have completed additional fellowship training specifically in the surgical, chemotherapeutic, and radiotherapeutic management of gynecologic cancers including ovarian, uterine, cervical, vulvar, and vaginal malignancies. Gynecologic oncologists serve a critical role in the care of patients whose reproductive health is affected by cancer. For patients of reproductive age, oncofertility discussions — addressing fertility preservation options before cancer treatment begins — are an important component of comprehensive cancer care. The practice coordinates with other specialists in the Knoxville area as needed for complex patient management.
Services and Treatments
- Surgical management of gynecologic malignancies (ovarian, uterine, cervical, vulvar, vaginal)
- Minimally invasive gynecologic oncology surgery (robotic, laparoscopic)
- Medical management of gynecologic cancers including chemotherapy coordination
- Fertility-sparing surgical approaches for eligible patients with early-stage cancers
- Management of complex pelvic conditions including endometriosis and advanced pelvic pathology
- Genetic counseling referrals for hereditary gynecologic cancer syndromes (BRCA, Lynch syndrome)
- Survivorship care planning including reproductive counseling
- Coordination with reproductive endocrinologists for oncofertility planning
- Second opinion consultations for patients with complex gynecologic oncology diagnoses
Laboratory and Success Rates
Knoxville Gynecologic Cancer Specialists is a surgical specialty practice and does not operate an IVF laboratory. ART outcome data is not applicable to this practice. Fertility preservation outcomes for patients undergoing cancer treatment — including egg freezing or embryo banking — depend on the reproductive endocrinology practice performing those procedures and on the patient's underlying health status. Patients should review the most current cycle-level data published by the CDC's ART Surveillance program and the SART Clinic Summary Report.
Patient Experience
The Parkside Drive location in west Knoxville places the practice in a professional medical office corridor near Farragut — one of Knoxville's most affluent and rapidly growing suburbs. The location is accessible from Kingston Pike and I-40, making it convenient for patients traveling from across Knox County and from surrounding communities including Oak Ridge, Maryville, and communities in Sevier, Anderson, and Loudon counties. Knoxville's role as East Tennessee's regional medical center means that the practice likely draws referrals from community hospitals and OB-GYN practices throughout the mountainous Appalachian region. The University of Tennessee Medical Center and Covenant Health system provide additional hospital-based resources for complex surgical and oncologic cases.
Considering At-Home Insemination?
Not every fertility journey begins in a clinic. For individuals who have completed gynecologic cancer treatment and been medically cleared to attempt conception, at-home insemination may be worth discussing with their care team. MakeAMom offers at-home insemination kits — including the BabyMaker kit for those with sensitivities, the CryoBaby kit designed for use with frozen or low-volume sperm, and the Impregnator kit for low-motility sperm — shipped discreetly to your door. With a reported 67% success rate among users, these kits provide an accessible, lower-cost entry point for those beginning their path to parenthood. MakeAMom's reusable kits are cost-effective compared to single-use alternatives and come with detailed instructions. That said, patients with a history of gynecologic cancer should always consult with both their oncologist and a board-certified reproductive endocrinologist before attempting any form of conception assistance.
Insurance and Financing
Tennessee does not mandate that health insurance plans cover fertility treatments such as IVF. Gynecologic oncology services — including surgery and chemotherapy — are typically covered by health insurance as medically necessary treatment for cancer. Oncofertility services — such as emergency egg freezing prior to cancer treatment — may or may not be covered depending on the specific insurance plan; patients should check with their insurer. Some cancer organizations and fertility preservation advocacy groups offer financial assistance or discounted fertility preservation services for patients undergoing cancer treatment who wish to preserve their fertility. Patients should ask the oncology practice's financial counselor about available resources.
Frequently Asked Questions
What is a gynecologic oncologist and how do they differ from a general OB-GYN? A gynecologic oncologist is an OB-GYN physician who has completed a three-to-four year fellowship in the medical and surgical management of gynecologic cancers. They are trained to perform complex debulking and reconstructive surgeries, administer intraperitoneal or intravenous chemotherapy, and manage the multi-modal care required for gynecologic malignancies. General OB-GYNs typically refer patients with confirmed gynecologic cancers to this subspecialty.
What are fertility-sparing options for patients with gynecologic cancer? For selected patients with early-stage gynecologic cancers, fertility-sparing approaches may be appropriate. For example, some patients with stage IA cervical cancer may be candidates for trachelectomy (cervix removal with uterus preservation) rather than hysterectomy. Some patients with low-grade, stage I ovarian cancer may have a single ovary removed while preserving the uterus and contralateral ovary. These decisions are highly individualized and require careful evaluation by a gynecologic oncologist.
What genetic cancer syndromes are relevant to gynecologic oncology? BRCA1 and BRCA2 mutations significantly increase the risk of ovarian and fallopian tube cancer. Lynch syndrome (hereditary nonpolyposis colorectal cancer, HNPCC) is the most common hereditary uterine cancer syndrome. Patients diagnosed with gynecologic cancers at a younger age, or those with a family history of multiple cancer types, may benefit from genetic counseling and testing to identify inherited risk.
When should an oncofertility consultation happen? Ideally, oncofertility consultation should occur before cancer treatment begins — before surgery, chemotherapy, or radiation that may affect fertility. Time is often limited, but even a brief emergency fertility preservation cycle (typically 10–14 days) may allow egg or embryo banking before treatment. Patients who have already completed treatment can still consult a reproductive endocrinologist about their remaining reproductive options.

