Main Line Fertility is located at 130 S Bryn Mawr Avenue in Bryn Mawr, Pennsylvania — in the affluent and medically rich Main Line corridor west of Philadelphia. With a 4.3-star rating from 224 patient reviews, the clinic is one of the most respected independent fertility practices in the Greater Philadelphia region, serving patients from the Main Line communities of Bryn Mawr, Ardmore, Haverford, Wayne, and Paoli, as well as patients commuting from Philadelphia proper and the New Jersey shore communities across the river. Main Line Fertility is an LGBTQ+-inclusive practice. Pennsylvania does not have a state fertility insurance mandate, though patients with certain employer-sponsored plans may have coverage depending on their insurer. For a full directory of Pennsylvania fertility clinics, visit the Pennsylvania fertility clinics directory.
Physicians and Clinical Team
Main Line Fertility is led by Dr. Michael Glassner, a board-certified reproductive endocrinologist who has practiced at this location for many years and who is recognized locally as one of the region's most experienced REI specialists. Dr. Glassner trained at leading academic centers and has maintained a clinical focus on individualized treatment planning and physician-patient continuity. The broader team includes nursing staff with fertility-specialty experience, sonographers, and laboratory embryologists who support the clinic's IVF program. Patients who value a practice where the same physician follows them throughout their care often cite Main Line Fertility's model as a meaningful difference from larger network or academic practices. Visit mainlinefertility.com or call (610) 526-8950 for current information.
Services and Treatments
- IVF with ICSI
- Frozen embryo transfer (FET)
- Preimplantation genetic testing (PGT-A and PGT-M)
- Intrauterine insemination (IUI) with donor or partner sperm
- Egg freezing for elective or medical fertility preservation
- Embryo banking and cryopreservation
- Donor egg IVF
- Donor sperm and donor embryo cycles
- Gestational carrier coordination
- Reciprocal IVF for same-sex female couples
- LGBTQ+ family building pathways
- Ovulation induction with oral agents and injectables
- PCOS evaluation and treatment
- Endometriosis and uterine factor assessment
- Recurrent pregnancy loss evaluation
- Male factor semen analysis
Laboratory and Success Rates
Main Line Fertility operates an on-site IVF laboratory at the Bryn Mawr location. The laboratory performs all embryology work including fertilization, blastocyst culture, genetic testing biopsy, and vitrification. Patients should ask for age-stratified live birth rate data during the consultation to understand how the clinic's outcomes compare for their age group. Patients should review the most current cycle-level data published by the CDC's ART Surveillance program and the SART Clinic Summary Report.
Patient Experience
Bryn Mawr is one of the most established communities on Philadelphia's western suburban corridor, home to Bryn Mawr Hospital, the Graduate School of Social Work, and a well-developed commercial district on Lancaster Avenue. The clinic at 130 S Bryn Mawr Avenue is easily accessible by car from Route 30, I-476, and the Blue Route, and the nearby Bryn Mawr SEPTA rail station on the Paoli/Thorndale line makes the practice accessible by regional rail from Center City Philadelphia — a meaningful option for city residents who prefer not to drive.
Main Line Fertility's model is built around physician continuity and personalized attention. Patients who have experienced larger, more bureaucratic fertility practices often remark on the difference: at Main Line, the physician who performs your initial consultation is typically the same physician who oversees your monitoring, retrieval, and transfer. This continuity reduces the sense of being handed off between providers and allows the care relationship to develop over time — important in a specialty where treatment may extend across many months.
The Main Line corridor's demographics — educated, often professionally successful, frequently delayed family building into the mid-to-late thirties — create a patient population that brings high expectations and sophisticated questions to fertility consultations. The clinic's approach to thorough explanation and transparent communication matches those expectations well, as reflected in its consistent patient ratings.
Considering At-Home Insemination?
Not every fertility journey begins in a clinic. At-home intracervical insemination (ICI) is a lower-cost, private option that suits patients with no known fertility diagnosis — including single parents by choice, same-sex couples, and people who want to try a few cycles before committing to clinical treatment.
At-home insemination kits like those from MakeAMom come with step-by-step instructions designed for donor or partner sperm. Kits are a one-time purchase that can be reused until conception succeeds, require no clinic visit, and arrive in plain, discreet packaging. Many patients use them as a first step while working toward a fertility consultation — or alongside ovulation tracking while they wait for an appointment slot.
If you have a known fertility diagnosis, have been trying for 12 months without success (six months if you're over 35), or your physician has already recommended IUI or IVF, a board-certified reproductive endocrinologist is the right next step.
Insurance and Financing
Pennsylvania does not have a state mandate requiring insurance plans to cover IVF. Coverage at Main Line Fertility depends entirely on the patient's specific employer-sponsored or individual health plan. Some large Philadelphia-area employers in healthcare, financial services, and education do include voluntary fertility benefits; patients should review their plan documents or ask HR. Main Line Fertility's billing team can assist with benefits verification. Financing options through medical lending programs are available. Patients coming from New Jersey — which does have a fertility insurance mandate — should confirm whether their New Jersey-regulated plan's benefits apply at an out-of-state provider.
Frequently Asked Questions
Is Main Line Fertility a solo practice or part of a larger network? Main Line Fertility is an independent practice, not part of a large network. This means patients receive care in a more intimate clinical environment with physician continuity built in. Dr. Glassner and his team manage a smaller patient volume than large network practices, which supports the personalized care model.
Can Philadelphia residents access the clinic without a car? Yes. The Bryn Mawr SEPTA station on the Paoli/Thorndale line is within walking distance of the clinic. Regional rail from Center City Philadelphia (Market East, Suburban Station, or 30th Street Station) connects directly to Bryn Mawr station, making the clinic accessible for city residents who commute by train.
Does Main Line Fertility work with known egg donors or sperm donors the patient has already identified? Yes. The clinic can coordinate cycles using known donors (people the patient already knows and has selected). The process involves medical screening of the donor and legal documentation — the clinic's team can walk patients through the requirements during a consultation.
What is the typical duration from first consultation to embryo transfer? The timeline varies based on diagnosis and treatment plan. A fresh IVF cycle from the start of injectable medications through embryo transfer is approximately 4-6 weeks. Additional time may be needed for diagnostic workup, genetic testing processing, or frozen cycle preparation. Your physician will give you a personalized timeline at the consultation.