PGT-M (Preimplantation Genetic Testing for Monogenic Disorders)

PGT-M allows couples who carry or are affected by a specific genetic condition — such as cystic fibrosis, sickle cell disease, or BRCA mutations — to test embryos before transfer and select those unaffected by the mutation.

The laboratory designs a custom probe for each couple's specific variant, which requires a preparation phase of several weeks before IVF begins. This makes PGT-M logistically more complex than PGT-A.

It is highly accurate (>98%) and enables families with known hereditary conditions to reduce the risk of passing a disease to their child without requiring prenatal testing after pregnancy.